By Topic

A comprehensive human chromosome 21 database

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)

The article presents a new, comprehensive, user-friendly chromosome 21 database driven by a built-in protein interaction prediction tool based on Markov random field (MRF) and GeneQuest, a novel easy-to-use user interface. The database contains a wide range of data including both in-house generated data (i.e., chromosome 21 orthologs) and data collected from other existing chromosome 21 databases (i.e., protein interactions, pathways, etc.). This article describes the underlying overall database design and data preparation, explains the underlying process of built-in protein-protein interaction prediction tool based on MRF including experimental results, presents details of the GeneQuest facilities, and illustrates the results and typical uses of the database

Published in:

Engineering in Medicine and Biology Magazine, IEEE  (Volume:26 ,  Issue: 2 )