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The association of CNVs with disease is of interest in medical genetics. This paper makes use single nucleotide polymorphism (SNP) to infer copy number variation (CNV). A microrray technology known as SNP-CGH (SNP-comparative genomic hybridization) is used to detect DNA CNV. Current SNP-CGH arrays contain > 100, 000 probes. The Illumina BeadChip has been designed for whole genome SNP genotyping applications. It can probe thousands of SNPs on one array and up to 30 replicates per SNP. The study shows that fluoresescence intensity signals are proportional to the amount of gDNA. SNPs in deleted or duplicated regions show decreased/elevated signals relative to normal regions. Signal processing using Bayesian hidden Markov model has been applied to BeadChip data to find CNVs.