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We develop mechanisms for reducing the effect of interference between users by means of controlling the degree of impulsiveness of their interference signals. Our analysis assumes spread-spectrum multiple-access, and in particular ternary CDMA signaling, whose interference statistics can be parameterized while keeping the desired de-spread signal fixed. We find the spreading patterns of the interferer and user which minimize the bit error rate (BER) at the user, as a function of the signal-to-interference signal-to-noise ratio matrix. The results are shown numerically, and in some extreme cases are supported by theoretic analysis. Finally we propose distributed protocols which try to approach the optimal operation points (i.e., pairs of spreading patterns) in the lack of central coordination.