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Automatic registration of images with translational, rotational, and scaling differences is discussed. To register two images from the same scene, first, the images are segmented and closedboundary regions in the images are extracted. Next, centers of gravity of closed-boundary regions are taken as control points and correspondence is established between the control points. Using this correspondence, the original images are then revisited and the segmentation process is refined in such a way that the obtained corresponding regions become optimally similar. This enables determination of centers of gravity of the regions up to subpixel accuracy. Finally, registration parameters are determined by the least squares error criterion.