By Topic

Repetitive Analog Computer for Analysis of Sums of Distribution Functions

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
F. W. Noble ; Lab. of Tech. Dev., Natl. Heart Inist., Natl. Institutes of Health, Bethesda, Md. ; J. E. Hayes ; M. Eden

Many experimental procedures yield curves which are sums of distribution functions. Examples of such curves include electrophoretic, diffusion, and ultracentrifugal patterns, absorption spectra, and curves from countercurrent distribution and from partition chromatography in either liquid or vapor phase. In a given type of curve, each of the component functions is identical to the others in form (for example Gaussian) but can have very different values of the parameters governing height, width, and position along the abscissa. We wish to determine the parameters for each component by an analysis of the sum curve. The computer to be described performs this analysis by synthesizing a number of distribution functions of the desired form, each with adjustable parameters, and presenting, on an oscilloscope, the sum of these functions for comparison with the experimental curve being analyzed. A match is made visually by adjustment of the various parameters. When a match has been obtained, the parameters of the component functions are read out, following a switching procedure which presents the individual functions in sequence.

Published in:

Proceedings of the IRE  (Volume:47 ,  Issue: 11 )