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Single nucleotide polymorphism data analysis - State-of-the-art review on this emerging field from a signal processing viewpoint

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3 Author(s)
Shih-chieh Su ; Southern California Univ., CA ; C. -c. Jay Kuo ; Ting Chen

The basic structural units of the genome are nucleotides. A single nucleotide polymorphism (SNP) is a mutation at a single nucleotide position. This paper discusses several major problems in SNP data analysis and review some existing solutions in this work. Generally speaking, a rich set of SNP analysis problems are cast in the signal processing framework. Our objective is to offer a state-of-the art review on this topic from a signal processing viewpoint so that researchers in the signal processing field can grasp the important domain knowledge to overcome the barrier between the two fields

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IEEE Signal Processing Magazine  (Volume:24 ,  Issue: 1 )