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A New Approach to Predicting Regulatory Elements in Dictyostelium Gene Expression

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4 Author(s)
Kim, J.H. ; Arkansas Univ., Little Rock, AR ; Daekwan Seo ; Yasunaga, M. ; Insook Kim

In current bio informatics, the prediction of transcriptional regulatory elements (TREs) is one of the major challenges. It is a key step toward deciphering entire genetic regulatory networks. The goal of this study is to predict TREs associated with four classes of developmentally regulated genes in dictyostelium discoideum (Dd). Applying a pattern recognition method to 5' untranscribed region of Dd sequences, the evaluation score (E-score) for each candidate TRE is calculated. Based on these E-scores and the proposed selection criteria, putative class-specific TREs are predicted in each developmentally regulated class of Dd

Published in:

Hybrid Information Technology, 2006. ICHIT '06. International Conference on  (Volume:1 )

Date of Conference:

9-11 Nov. 2006