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Formation of Microdroplets in Liquids Utilizing Active Pneumatic Choppers on a Microfluidic Chip

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2 Author(s)
Cheng-Tso Chen ; Dept. of Eng. Sci., Nat. Cheng Kung Univ., Tainan ; Gwo-Bin Lee

Monodispersed emulsions are of great significance for a variety of applications. The current study reports a new microfluidic system capable of formation of microdroplets in liquids for emulsification applications. This new emulsion chip can precisely generate uniform droplets using a novel combination of hydrodynamic-focusing and liquid-chopping techniques. Experimental data show that microdroplets with diameters ranging from 6 to 100 mum with a variation less than 3% can be precisely generated. The size of the droplets is tunable using three approaches including adjusting the relative sheath/sample flow velocity ratios, the applied air pressure and the applied chopping frequency. Moreover, focusing and chopping of multiple flows has been demonstrated to increase the emulsion process throughput

Published in:

Journal of Microelectromechanical Systems  (Volume:15 ,  Issue: 6 )