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Hall Biosensor With Integrated Current Microstrips for Control of Magnetic Beads

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6 Author(s)
Kumagai, Y. ; Dept. of Electr. & Electron. Eng., Tokyo Inst. of Technol. ; Togawa, Kiyoshi ; Sakamoto, Satoshi ; Abe, Masanori
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Magnetic labeling of biomolecules shows potential as an alternative to fluorescence for monitoring molecular interactions associated with DNA hybridization and antibody-antigen analysis. Current carrying microstrips were integrated with micro-Hall biosensors to manipulate and collect superparamagnetic beads by field gradients generated due to direct currents passed through the strips. Magnetic beads with 2.8-mum diameters were collected over the active regions of AlGaAs/InGaAs heterostructure micro-Hall biosensors and detected in real time. The integration of current-carrying microstrips with Hall biosensors will decrease the time required for detecting biomolecular recognition processes in Hall sensor-based bioscreening platforms

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Magnetics, IEEE Transactions on  (Volume:42 ,  Issue: 12 )