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Experimental verification of theoretical in vivo ultrasound heating using cobalt detected magnetic resonance

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4 Author(s)
Smith, N.B. ; Dept. of Electr. & Comput. Eng., Illinois Univ., Urbana, IL, USA ; Webb, A.G. ; Ellis, D.S. ; O'Brien, W.D., Jr.

Conventional methods of measuring heating in vivo are invasive and therefore interfere with heat propagation. For the first time, ultrasound-induced temperature increases in living specimens have been estimated theoretically and measured experimentally using a noninvasive technique. In vivo ultrasound-induced temperature increases in the livers of rats show consistent results between: (1) a theoretical ultrasound point-source solution for a measured ultrasound source power of 4.3 W (2/spl deg/C) and (2) a sensitive noninvasive magnetic resonance method with the cobalt (III) nucleus as a probe (2.0/spl plusmn/1.2/spl deg/C).<>

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Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on  (Volume:42 ,  Issue: 4 )