Experimental verification of theoretical in vivo ultrasound heating using cobalt detected magnetic resonance

Conventional methods of measuring heating in vivo are invasive and therefore interfere with heat propagation. For the first time, ultrasound-induced temperature increases in living specimens have been estimated theoretically and measured experimentally using a noninvasive technique. In vivo ultrasound-induced temperature increases in the livers of rats show consistent results between: (1) a theoretical ultrasound point-source solution for a measured ultrasound source power of 4.3 W (2/spl deg/C) and (2) a sensitive noninvasive magnetic resonance method with the cobalt (III) nucleus as a probe (2.0/spl plusmn/1.2/spl deg/C).<
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