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Biotechnology-based recognition elements

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1 Author(s)
J. S. Schultz ; Center for Biotechnol. & Bioeng., Pittsburgh Univ. Sch. of Med., PA, USA

The author discusses technology, applications, and opportunities for biosensors. The following topics are considered: the shape of the myoglobin molecule; a schematic structure of an antibody showing the different regions of the molecule; the form of the membrane-bound acetylcholine receptor protein; forces responsible for interactive behavior between receptors and ligands; a photolithographic technique for the production of a peptide library on a chip; the principle of affine chromatography; the structure of a glucose electrode developed by Leland Clark; interferences with an enzyme-based glucose biosensor; components of biosensors; a glucose sensor based on fiber optics.<>

Published in:

IEEE Engineering in Medicine and Biology Magazine  (Volume:14 ,  Issue: 2 )