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Local threshold for segmented attenuation correction of PET imaging of the thorax

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4 Author(s)
Xu, M. ; Mallinckrodt Inst. of Radiol., St. Louis, MO, USA ; Luk, W.K. ; Cutler, P.D. ; Digby, W.M.

A local threshold for segmented attenuation correction technique has been developed for positron emission tomography using short (2-3 minutes) post-injection transmission scans. The technique implements an optimal threshold method on localized histograms to get pseudo-anatomic segmentation on transmission images. Theoretical values of attenuation coefficients are assigned to corresponding anatomic regions. Emission images are reconstructed using attenuation correction factors computed by forward-projecting segmented transmission images. Phantoms and clinical cardiac images are studied using this technique. The technique corrects emission images with accuracy similar to the standard, pre-injection method, reduces noise in the corrected emission images, and offers the potential for increased patient throughput by enabling shorter, post-injection data acquisition

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Nuclear Science, IEEE Transactions on  (Volume:41 ,  Issue: 4 )