Cart (Loading....) | Create Account
Close category search window

Engineering in genomics/spl minus/combinatorial methods for DNA physical mapping

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

1 Author(s)
Pevzner, P.A. ; Dept. of Comput. Sci., Pennsylvania State Univ., University Park, PA, USA

To build a physical map biologists use different biochemical techniques to derive indirect information about the map and combinatorial methods to reconstruct the map from these data. Several experimental approaches to DNA physical mapping exist, each with its own advantages and disadvantages. They lead to different combinatorial problems but unfortunately, for most of these problems polynomial algorithms are still unknown; moreover, many of them are NP-complete. To solve some of these problem a number of combinatorial techniques have been suggested, in particular: homometric sets analysis, interval graphs, flows in networks, separation theory and minimum cycles mean in graphs. The author discusses: small-scale mapping; probed partial digestion; progress toward a basic map.<>

Published in:

Engineering in Medicine and Biology Magazine, IEEE  (Volume:13 ,  Issue: 1 )

Date of Publication:

Feb.-March 1994

Need Help?

IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.