By Topic

Reconstruction methods for quantitative brain SPECT

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
B. M. W. Tsui ; Univ. of North Carolina, Chapel Hill, NC, USA ; X. D. Zhao ; Z. J. Cao ; E. C. Frey

The reconstruction methods currently available for use in quantitative brain SPECT (single photon emission computed tomography) imaging were studied. The conventional reconstruction methods are based on the filtered backprojection algorithm. Assuming uniform attenuation, the Chang algorithm is effective in attenuation compensation. The collimator response can be compensated for by a restoration filter with an average collimator response function. Scatter compensation can be achieved by the dual window subtraction method or by incorporating an average scatter response function in the restoration filter. The dual window subtraction method is an approximate but efficient means of providing projection data which are compensated for scatter. The iteration reconstruction method can be applied to these data for addition compensation for attenuation and the spatially variant collimator response. The latter is accomplished by incorporating the exact model of attenuation and detector response function in the projector/backprojector of the iterative algorithm. A 3-D brain phantom was used in the evaluation study. The images obtained from various reconstruction methods were compared for quantitative accuracy with respect to the known 3-D phantom activity distribution.<>

Published in:

Nuclear Science Symposium and Medical Imaging Conference, 1991., Conference Record of the 1991 IEEE

Date of Conference:

2-9 Nov. 1991