Scheduled System Maintenance:
On Monday, April 27th, IEEE Xplore will undergo scheduled maintenance from 1:00 PM - 3:00 PM ET (17:00 - 19:00 UTC). No interruption in service is anticipated.
By Topic

Distribution models of recirculating lymphocytes

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

2 Author(s)
Farooqi, Z.H. ; Dept. of Electr. & Comput. Eng., Oregon State Univ., Coarvallis, OR, USA ; Mohler, R.R.

Linear time-invariant, linear time-variant, and linear time-delay models are compared to a more accurate nonlinear model for the distribution of recirculating lymphocytes to various relevant organs of the immune process. The models are based on various degrees of approximation to the complex nonNewtonian tubule flow and tissue diffusion phenomena. From the measured data, it is apparent that the basic premise of cel-population conservation is not valid within the organs measured. In other words, counts are lost due to nonrecirculation and removal, natural death, and migration to organs not measured. The analysis does successfully decouple the recirculating (passive) lymphocyte dynamics from the dynamic response (and active migration) which is due to antigenic (alien substance) stimulation.

Published in:

Biomedical Engineering, IEEE Transactions on  (Volume:36 ,  Issue: 3 )