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Transfection by electroporation: cell gene transfer using electrical impulses, a new process in blood cancer research

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4 Author(s)
Jamieson, R.D. ; Electricorp, New Plymouth, New Zealand ; Bodger, M.P. ; Bodger, P.S. ; Baran, D.

Isolated genetic material can be transferred into a host cell through its membrane by the application of an appropriate electrical impulse to the cell. The authors describe a three-stage impulse generator designed to transfect viral genes into human blood cells, to aid scientists in their research into blood cancers by immortalizing the cells. Trials on samples from a terminal cancer patient resulted in successful electroporation of an antibiotic-resistant gene.<>

Published in:

Physical Science, Measurement and Instrumentation, Management and Education, IEE Proceedings A  (Volume:136 ,  Issue: 1 )

Date of Publication:

Jan. 1989

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