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In this paper, we propose an office layout support system using interactive genetic algorithm. In the proposed system, some conditions such as size and form of room, size and position of window and door, and the number of desks, shelves and printers and so on are given by users, some layout plans which satisfy the conditions are generated by genetic algorithm. In this system, desks are packed per group, and relation between arrangement plans for every group is expressed in the sequence-pair representation. We carried out a series of computer experiments in order to demonstrate the effectiveness of the proposed system and confirmed that the proposed system can generate various layout plans.