Cart (Loading....) | Create Account
Close category search window
 

Microdosimetric characteristics of micro X-ray beam for single cell irradiation

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

6 Author(s)
Kuchimaru, T. ; Div. of Electr., Electron. & Inf. Eng., Osaka Univ., Japan ; Sato, F. ; Higashino, Y. ; Shimizu, K.
more authors

A tabletop micro X-ray beam irradiation system has been developed to study radiation effects on living cells. The microbeam system is composed of a micro focus X-ray tube, a capillary for X-ray guide, an X-ray semiconductor detector for fluorescent X-ray analysis, and an inverted microscope. A beam profile measurement was performed and the size of the focused beam was 10 μm in diameter [full-width at half-maximum (FWHM)] with a divergence of 5.1 mrad. The data on the microbeam measurement were approximately in agreement with a simulation of X-ray optical traces for the capillary. In addition, the microdosimetric characterization for single cell irradiation was performed with the beam profile measurement and a photon-electron transport simulation. The maximum of the dose rate for the sample cells set in the system was estimated to be 0.05 Gy/s. In a preliminary experiment, single yeast cells were irradiated with the X-ray microbeams, and the data on the survival rate of the cell samples for the X-ray doses were obtained. Then, the microbeam irradiation system is useful to investigate the radiation effects on the living cells.

Published in:

Nuclear Science, IEEE Transactions on  (Volume:53 ,  Issue: 3 )

Date of Publication:

June 2006

Need Help?


IEEE Advancing Technology for Humanity About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies

A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2014 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.