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In this paper, an efficient digital implementation of multicarrier transmission scheme based on generalized discrete Fourier transform (DFT) filter banks is presented for multicarrier code-division multiple-access (MC-CDMA) systems. Generalized DFT filter banks has been traditionally discussed for very high-speed digital subscriber lines (VDSL) wireline systems, received interest also for wireless applications. The design of the generalized DFT modulated filter banks is investigated and its fast implementation is derived in the time-domain for arbitrary integer sampling rate. Through the utilization of the generalized DFT modulated filter banks, one or more subcarriers, even noncontiguous subcarriers can be easily supported by system in both uplink and downlink, which facilitates the users to access the network in a frequency-division multiple-access manner. Simulation results show that the overall bit-error-rate performance of the proposed multicarrier transmission scheme well approaches that of a single-carrier system due to the negligible intercarrier interference introduced by an appropriate design of the generalized DFT modulated filter banks.