Referenced Items are not available for this document.
This paper introduces an integrated circuit (IC)/microfluidic hybrid system for magnetic manipulation of biological cells. The hybrid system consists of an IC and a microfluidic system fabricated on top. Biological cells attached to magnetic beads are suspended inside the microfluidic system that maintains biocompatibility. The IC contains a microcoil array circuit that produces spatially-patterned microscopic magnetic fields. Programmable, rapid reconfiguration of the field pattern made possible by the IC allows an efficient simultaneous manipulation of multiple individual bead-bound cells with precise position control. Two prototypes, SiGe/microfluidic and CMOS/microfluidic hybrid systems, validate the proposed approach.
Published in:
Solid-State Circuits, IEEE Journal of
(Volume:41
,
Issue:
6
)
Date of Publication: June 2006
- Page(s):
- 1471 - 1480
- ISSN :
- 0018-9200
- INSPEC Accession Number:
- 8935015
- Digital Object Identifier :
- 10.1109/JSSC.2006.874331
- Product Type:
- Journals & Magazines
- Date of Current Version :
- 30 May 2006
- Issue Date :
- June 2006
- Sponsored by :
- IEEE Solid-State Circuits Society
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