The short and highly degenerate nature of transcription factor (TF) binding sites makes their identification a challenging task. We propose a new method based on templates for identifying TF binding sites. Templates account for sequence structure and nucleotide polymorphisms present in TF binding sits providing them with a greater discriminatory capability to methods based on sequence homology
Published in:
Statistical Signal Processing, 2005 IEEE/SP 13th Workshop on
Date of Conference: 17-20 July 2005