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Finding transcription factor binding sites in DNA sequences: a template based approach

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2 Author(s)
Gunewardena, S. ; Comput. Lab., Oxford Univ. ; Zhaolei Zhang

The short and highly degenerate nature of transcription factor (TF) binding sites makes their identification a challenging task. We propose a new method based on templates for identifying TF binding sites. Templates account for sequence structure and nucleotide polymorphisms present in TF binding sits providing them with a greater discriminatory capability to methods based on sequence homology

Published in:

Statistical Signal Processing, 2005 IEEE/SP 13th Workshop on

Date of Conference:

17-20 July 2005

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