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Motion-compensated dynamic image reconstruction for gated cardiac SPECT

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4 Author(s)
Mingwu Jin ; Dept. Electr. & Comput. Eng., Illinois Inst. of Technol., Chicago, IL ; Yongyi Yang ; Wernick, M.N. ; King, M.A.

In this paper we propose a unified image reconstruction procedure for dynamic images from traditional gated SPECT acquisition. We divide the cardiac cycle into a number of gate intervals as in gated SPECT, but treat the tracer distribution for each gate as a time-varying signal. By using dynamic expectation maximization and motion-compensated temporal regularization, our reconstruction procedure can produce an image sequence that shows both cardiac motion and time-varying tracer distribution simultaneously. We simulated gated cardiac perfusion imaging using the gated mathematical cardiac-torso (gMCAT) phantom with Tc99m-Teboroxime dynamics. Our experimental results show that the proposed methods can produce more accurate reconstruction of gated dynamic images than independent reconstruction of individual gate frames with spatial smoothness alone

Published in:

Biomedical Imaging: Nano to Macro, 2006. 3rd IEEE International Symposium on

Date of Conference:

6-9 April 2006