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Simulation of the human cardiovascular system for real-time physical interaction with an assist device

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4 Author(s)

In the development of left ventricular assist devices (LVADs), numerical simulations of the cardiovascular (CV) system have been widely used. Further, electrohydraulic simulations have been developed to evaluate the performance of a physical LVAD prototype against a numerical model of the CV system. The effects of dynamic cardiac compression (DCC) have been less well modeled. This paper considers the interaction between a DCC device and a closed-loop numerical model of the cardiovascular system, which is specifically developed. The model is operated in real-time, and interfaced to the physical assist device for realistic testing. Assist control strategies are compared: constant pressure DCC, and volume-proportional pressure to simulate cardiomyoplasty. The model shows that applying equal pressure to both ventricles causes inflation of the left ventricle

Published in:

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Date of Conference:

17-18 Jan. 2006