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Detection of colon cancer by laser induced Fluorescence and Raman spectroscopy

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5 Author(s)
Xiaozhou Li ; Dept. of Phys., Shenyang Ligong Univ. ; Xinyu Li ; Ming Lei ; Deli Wang
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Laser-induced fluorescence and Raman spectroscopy of serum for detect colon cancer was investigated in this paper. The difference to serum spectrum was discovered. Three Raman peaks were consistently observed from normal blood serum emission using 488.0 nm and 514.5 nm excitation of an Ar-ion laser. While no Raman peak or slight Raman peaks were detected from colon cancer's cases. In addition, the red shift of fluorescence peak and decrease of fluorescence intensity are founded after samples radiated by laser. 65 colon cancer cases are investigated in this paper. Through three parameters we obtained an accuracy of 83.5% compared to clinical diagnosis. These results have important reference values to explore the method of Raman spectrum and for diagnosis of cancer

Published in:

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Date of Conference:

17-18 Jan. 2006