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This study aimed at evaluating the effects of mechanical repositioning, obtained by the increase in seat-to-back (STB) and system tilt angles, on the position of the pelvis with spinal-cord injured subjects seated in a wheelchair. The noninvasive method used combined magnetic resonance imaging (MRI) images of the whole pelvis obtained in a supine posture and ultrasound images of the pelvic iliac crests obtained in four seating positions. The matching of the two image data sets enabled the location of fourteen pelvic landmarks in the seated positions. From these landmarks, the pelvic tilt, obliquity, and transverse rotation, and the three-dimensional (3-D) motion of the pelvis were calculated. Results showed that the increase in STB angle is not equal to the calculated increase in pelvic tilt and that the pelvis rotated posteriorly, moved forward and downwards. An increase in the system tilt moved the pelvis rearwards and downwards, which counterbalanced the movement seen with the increase in STB. At the return to the first position, no significant changes were observed in the pelvis' position and orientation compared to the initial posture. Results also demonstrated the importance in calculating the total 3-D rotations and translations to characterize adequately the pelvic movement.