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Decision Support System (DSS) is developed for Karachi Nuclear Power Plant (KANUPP) for off-site emergency management. By only one click to get all information about Karachi Emergency Relief Plan (KERP) document, countermeasures on the basis of priority, economic cost and social behavior of the affected area by Nuclear hazard. Also share work with others across the Network. This computer-based expert system can also provide. System is a distributed application, which consists of a comprehensive database in SQL 7.0 server and a user-friendly environment in Microsoft Visual Basic 6.0.