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Influence of sensor arrangements and scintillator crystal properties on the 3D precision of monolithic scintillation detectors in PET

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5 Author(s)
Ojala, P. ; Dept. of Med. Radiat. Phys., Stockholm Univ. ; Bousselham, A. ; Eriksson, L. ; Brahme, A.
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This paper reports the characterization and comparison of different sensor configurations for monolithic scintillation crystals via the calculation of a figure of a merit based on statistical (Fischer) information. The optimal precision of maximum likelihood determinations of interaction positions, i.e. where annihilation photons are absorbed in a monolithic (LSO) crystal, is approximated throughout a crystal block via Fischer information (related to the width of the maximum likelihood distribution) evaluated at a grid of points. Realistic positions and thus realistic distributions of points of interaction are estimated by applying a maximum likelihood algorithm to Monte Carlo data. The algorithm was based on pattern recognition using a Monte Carlo generated lookup table and the least square method. The precision of this method is compared with the optimal (Cramer-Rao) limit for selected points

Published in:

Nuclear Science Symposium Conference Record, 2005 IEEE  (Volume:5 )

Date of Conference:

23-29 Oct. 2005

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