By Topic

To accelerate multiple sequence alignment using FPGAs

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

5 Author(s)
Xu Lin ; National Res. Center for Intellegent Comput. Syst., Chinese Acad. of Sci., Beijing ; Zhang Peiheng ; Bu Dongbo ; Feng Shengzhong
more authors

Multiple sequence alignment is a fundamental and challenging problem in computational molecular biology. ClustalW, the most widely used multiple sequence alignment software, performs very slowly on hundreds of sequence. Here, we analyze the algorithm complexity of ClustalW as well as the time profile in practice, and then propose a strategy which uses the reconfigurable hardware FPGA to accelerate ClustalW. Comparison with other coarse-grained parallel strategies demonstrates a fine speedup of this strategy and savage of computing resource

Published in:

High-Performance Computing in Asia-Pacific Region, 2005. Proceedings. Eighth International Conference on

Date of Conference:

1-1 July 2005