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This paper investigates an adaptive space-time equalisation (STE) assisted multiuser detection scheme for multiple-antenna aided multiuser systems. A minimum bit error rate (MBER) design is compared with the standard minimum mean square error (MMSE) design. It is shown that the MBER design provides significant performance enhancement, in terms of achievable system bit error rate, over the MMSE design for the multiple-antenna assisted multiple-input multiple-output communication scenario. Adaptive implementation of the MBER STE is realised using a stochastic gradient based least bit error rate algorithm, which is demonstrated to consistently outperform the adaptive least mean square based STE.