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The simultaneous wireline (600 MHz) and wireless (5.5 GHz) transmission of data over cable service interface specification (DOCSIS) signals in a hybrid fiber-radio access network is presented. The DOCSIS signal wireless replica is generated by means of an optical harmonic up-conversion technique based on a dual-drive Mach-Zehnder modulator. The optical signal is fed to a base station (BS) where a packaged asymmetric Fabry-Pe´rot modulator/detector acts simultaneously as a photodetector and an optical modulator. At the BS, the DOCSIS signals can be fed either to a wireline or a wireless access network, in a highly flexible approach. Full-duplex operation has been demonstrated for both access types, including indoor wireless transmission.