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A high-throughput adaptive computing infrastructure for bioinformatics research

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2 Author(s)
Pineo, S. ; Celera Genomics, Rockville, MD, USA ; Zhengyu Wang

To support our company's bioinformatics research and product development we developed the Celera computing analysis pipeline infrastructure (CCAPI). The N-tiered architecture, which includes a Web based user interface, an Oracle database, and a network of hundreds of CPUs, allows us to perform complex and compute-intensive data processing and analysis on genomic content in a cost-effective way. Developed using Perl, Java/JSP, Oracle's AQ and Platform LSF, CCAPI creates an adaptive and scalable computing framework that supports task decomposition and parallelization, optimizes computing resource allocation, facilitates the integration of proprietary and third-party applications, and supports automatic error detection and recovery.

Published in:

Systems Engineering, 2005. ICSEng 2005. 18th International Conference on

Date of Conference:

16-18 Aug. 2005