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Low-loss optical fibers are now indispensable transmission media for transmission systems. Recently, the ultralow-loss performance for long transmission systems, the water-loss-free performance for wide-band wavelength-division-multiplexing (WDM) systems, the hydrogen-loss-insensitive performance for system reliability, and the bending-loss-insensitive performance for access or indoor applications have attracted much interest. In this regard, pure-silica-core fibers (PSCFs) are suitable, and unprecedented low-loss PSCFs have been successfully fabricated. This paper introduces the recent progress of low-loss PSCFs and their possible impact on transmission systems.