Skip to Main Content
Task specific spiking activity that is selective for specific perceptions and actions is observed in the pre frontal cortex (PFC) of primates and rats during goal-directed behavior. A spiking neuron model of minicolumn circuits in PFC has been shown to successfully replicate the performance and categories of selective neuronal responses recorded in a primate visual discrimination task. The model provides a biological implementation of the action selection process used in reinforcement learning theory. Using this model, we propose a mechanistic explanation based on the reuse of previous encoding in PFC minicolumns for the ability to find short-cuts during the learning of some novel goal-directed tasks, but not others.