By Topic

Investigation of near-infrared autofluorescence imaging for the detection of breast cancer

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Demos, S.G. ; Lawrence Livermore Nat. Lab., CA, USA ; Bold, R. ; White, Rd.V. ; Ramsamooj, R.

Detection of breast cancer in fresh tissue obtained from surgery is investigated using near-infrared autofluorescence imaging under laser excitation at 532 and 632.8 nm. The differences in intensity between the three main components of breast tissue (cancer, fibrous, and adipose) are estimated and compared to those obtained from cross-polarized light scattering images recorded under polarized illumination at 700 nm. The optical spectroscopic images for each tissue sample were subsequently compared with the histopathology slides. The experimental results indicate that the intensity of the near-infrared emission is considerably different in breast cancer compared to that of the adjacent nonneoplastic tissues (adipose and fibrous tissue). The experimental results suggest that 632.8-nm excitation offers key advantages compared to 532 nm excitation.

Published in:

Selected Topics in Quantum Electronics, IEEE Journal of  (Volume:11 ,  Issue: 4 )