A parallel algorithm for clustering protein-protein interaction networks

The increasing availability of interaction graphs requires new resource-efficient tools capable of extracting valuable biological knowledge from these networks. In this paper we report on a novel parallel implementation of Girvan and Newman's clustering algorithm that is capable of running on clusters of computers. Our parallel implementation achieves almost linear speed-up up to 32 processors and allows us to run this computationally intensive algorithm on large protein-protein interaction networks. Preliminary experiments show that the algorithm has very high accuracy in identifying functional related protein modules.