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With the convergence of mobile and fixed communication networks, mobile users are increasingly demanding applications offering the same quality of service (QoS) as provided by wired access. High-speed time division duplex access mode is typical of high-speed mobile communication systems in order to simultaneously handle real-time, interactive, and best effort traffic classes. This paper proposes a medium access control (MAC) protocol that makes efficient use of radio resources for access. The proposed protocol, named dynamic-time division duplexing (D-TDD), is based on a multiple-access TDD air interface capable of supporting uplink and downlink traffic asymmetries. Validation of the D-TDD good performance was achieved by comparison with an ideal scheme and a different MAC protocol recently proposed in the literature on this subject.