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Biodistribution of chitosan-based magnetite suspensions for targeted hyperthermia in ICR mice

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9 Author(s)
Dong-Hyun Kim ; Dept. & Res. Inst. of Dental Biomaterials & & Bioeng., Yonsei Univ. Coll. of Dentistry, Seoul, South Korea ; Se-Ho Lee ; Ki-Hyeong Im ; Kyoung-Nam Kim
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Magnetite and the chitosan-based magnetite suspensions were synthesized by spray-coprecipitation. In the 2 wt% chitosan-based magnetite suspension, the zeta-potential value was lower value at 5.6 mV relative to other concentrations of magnetic suspension. The chitosan-based magnetic suspension with a zeta potential close to zero showed increased circulation time in biodistribution of Institute of Cancer Research mice.

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Magnetics, IEEE Transactions on  (Volume:41 ,  Issue: 10 )