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Ultrasensitive nanogap biosensor to detect changes in structure of water and ice

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3 Author(s)
Nevill, J.T. ; Dept. of Bioeng., California Univ., Berkeley, CA, USA ; Jeong, K.H. ; Lee, L.P.

Understanding how water behaves within nanoscale structures is critical in deciphering biological information. For example, water plays a key role in protein structure and function, cell architecture, and cell function. We present a unique nanogap biosensor that is capable of detecting changes in the structure of water and ice. Using dielectric spectroscopy inside a nanoscale cavity between two electrodes, we observe the structural changes in a network of small molecules such as water. We also demonstrate the effectiveness of a nanogap biosensor on detecting the changes in structure of water as it freezes under different ionic conditions.

Published in:

Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05. The 13th International Conference on  (Volume:2 )

Date of Conference:

5-9 June 2005