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Most current resource management algorithms are confined to a single layer of the network protocol stack, which leads to an inferior system performance. We propose a joint MAC-PHY layer resource allocation algorithm. The proposed algorithm jointly optimizes the bandwidth and power allocation through an integrated design of packet scheduling, subcarrier allocation, and power control. Analytical and numerical results show that the proposed algorithm is able to provide the same QoS and fairness guarantee as fair queueing systems do in a wired channel. Meanwhile, the power efficiency and system performance are significantly improved compared to traditional systems where resources are allocated based on a strict layering architecture.