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This paper proposes a new method based on pitch synchronous wavelet transform (PSWT), used for denoising ECG from noisy components. In this paper, we focus on the EMG frequently present in the ECG. This representation is based on a modelling concept, which is able to capture, period-to-period fluctuations of the signal by means of basis elements that are comb-like in the frequency domain. The application of this method on the corrupted signal permits to recover the denoised ECG. The performance of the proposed technique is evaluated on a variety of ECG signals (synthetic and real data) and experimental results show the accuracy of the proposed technique for all corrupted ECG tested.