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Optimizing sequential dual tracer P.E.T. studies using a combined 2D/3D imaging protocol

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6 Author(s)
Wilson, J.W. ; Dept. of Radiol., Duke Univ. Med. Center, Durham, NC, USA ; Turkington, T.G. ; Colsher, J.G. ; Borges-Neto, S.
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We have investigated a combined 2D/3D protocol for minimizing contamination in dual tracer P.E.T. studies in which the tracers are administered on a timescale that is short compared to the half-lives. We have performed a series of phantom studies on an Advance and a Discovery ST (GE Healthcare Technologies), using a torso phantom with cardiac insert (Data Spectrum Corporation) to simulate a combined FDG and NH3 scan protocol for a patient with ischemia. The phantom was imaged in a series of alternating 2D/3D acquisitions as it decayed over 6 half-lives. By comparing 2D and 3D images, we have verified that 3D images are of comparable accuracy to 2D images, even with realistic out-of-field activity challenging the 3D scans. Based on scan and image statistical quality, we have recommended optimal doses for maximizing the image quality of both scans.

Published in:

Nuclear Science Symposium Conference Record, 2004 IEEE  (Volume:6 )

Date of Conference:

16-22 Oct. 2004