By Topic

Proteins and their shape strings

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$33 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
R. E. Ison ; Dept. of Comp. Sci. & Eng., Colorado Univ., Denver, CO, USA ; S. Hovmoller ; R. H. Kretsinger

The paper presents an exemplary computer representation of protein structure. The paper described how the configurations of protein backbone turns can be recovered from shape-string (sequence of symbols) descriptions, which are compressed and approximate, by looking them up in a table. Although they are used internally in many algorithms, shape strings are not generally regarded as an annotation that humans should read. Protein structure is much more conserved by evolution than sequence is. Shape strings can be very revealing to the human eye and should identify distant homologues whose sequences have diverged in the fog of time.

Published in:

IEEE Engineering in Medicine and Biology Magazine  (Volume:24 ,  Issue: 3 )