By Topic

Modeling effects of infarction on cardiac function with dynamic finite element analysis

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Rumei Dong ; Biomed. Eng. Program, Rhode Island Univ., Kingston, RI, USA ; Ying Sun ; Vetter, F.J. ; Chiaramida, S.A.

A computational model has been developed that combines a 3D finite element model (FEM) of the left ventricle (LV) with an electrical analog model of the circulatory system. The model is used to assess the effects of infarction on LV function. LV geometry is modeled as a truncated ellipsoid. The stress-strain relationship for each element is assumed to be linear but with a time-varying Young's modulus. For a given LV pressure (Plv) generated by the electrical analog model, LV volume (Vlv) is determined by a 3D model constructed from multiple 2D FEM slices. The left ventricular elastance (Elv), determined by Plv over Vlv, is used to drive the electrical analog model. Time-varying Young's modulus functions over a cardiac cycle are assigned to normal and infarct finite elements, defining the infarct zone for a certain size and location. The model provided good representations of the LV geometry for normal and infarct cases. The LV ejection fraction, pressure, and volume curves were consistent with typical clinical observations. The dynamic finite element model developed in this study is effective and computationally efficient. The model can be used to relate regional LV impairments to overall circulatory dynamics.

Published in:

Bioengineering Conference, 2005. Proceedings of the IEEE 31st Annual Northeast

Date of Conference:

2-3 April 2005