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Deterministic Boolean networks (DBN) modeling of molecular biology: DNA replication

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4 Author(s)
Yeol, J.W. ; Dept. of Mech., Aerosp., & Manuf. Eng., Polytech. Univ. Brooklyn, NY, USA ; Samarrai, W. ; Barjis, I. ; Ryu, Y.S.

In this paper, we introduce a new method of modeling tool for a biological process -central dogma. The deterministic Boolean Network (DBN) is used as a modeling tool of the whole process, which enables us to simulate, analyze, and manipulate (in the future) at our disposal. From DNA to protein via RNA is the one of most well-known biological process, sometimes called central-dogma. Most of biological processes are deterministic and ruled by very precise commands, including control directions. These two common facts tell that it is the key in understanding biological processes to represent and analyze the flow of data of biology. As a result, the modeled process is easy to understand and to be implemented as a simulator to make students understood in classes; analyze and predict the process for researchers in near future.

Published in:

Bioengineering Conference, 2005. Proceedings of the IEEE 31st Annual Northeast

Date of Conference:

2-3 April 2005