By Topic

Integrated-optic surface-plasmon-resonance biosensor using gold nanoparticles by bipolarization detection

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

3 Author(s)
Tzyy-Jiann Wang ; Inst. of Electro-Opt. Eng., Nat. Taipei Univ. of Technol., Taiwan ; Cheng-Wei Tu ; Fu-Kun Liu

A new integrated-optic surface-plasmon-resonance (SPR) biosensor using gold nanoparticles with the ability of bipolarization interrogation is demonstrated. Although the previous SPR biosensor using gold nanoparticles can excite the surface plasma wave by the TM- and the TE-polarized lightwave, the sensitivity to the environmental index change for the TE-polarized lightwave is too low to be useful. The new integrated-optic SPR biosensor with a ridge waveguide structure can produce the obvious SPR wavelength shifts varied with the analyte concentration for two orthogonal polarizations. Therefore, two kinds of analytes can be separately detected by the TM- and the TE- polarized modes in one SPR biosensor, and the number of detectable biomaterials by the biosensor array in one chip can be doubled. This SPR biosensor is designed for the concentration measurement of beta-blocker, which is a remedy for heart disease. In the linear operation range, the SPR wavelength increases with the concentration of beta-blocker at a rate of 0.073 and 0.029 nm/ppm for the TM- and the TE- polarized modes, respectively.

Published in:

Selected Topics in Quantum Electronics, IEEE Journal of  (Volume:11 ,  Issue: 2 )