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Extracellular Optical Recording Configuration for Neuronal Action Potential Detection by using Surface Plasmon Resonance: Preliminary Experiment

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7 Author(s)
Hyoungwon Baac ; Nano-Bioelectron. & Syst. Res. Center, Seoul Nat. Univ. ; Sang Beom Jun ; Turner, J.N. ; Shain, W.
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We propose an extracellular optical recording configuration for neuronal action potential detection by using surface plasmon resonance (SPR). The method does not use fluorescence dyes but still taking advantages of optical recording. As a preliminary experiment, the electrochemical SPR effect without neurons was investigated. This showed that a high resolution SPR setup (10-4~10~5 angular shift or more) is required to overcome noise and improve SPR signal. Several issues for neural signal recording are addressed to modify SPR optical configuration

Published in:
Neural Engineering, 2005. Conference Proceedings. 2nd International IEEE EMBS Conference on

Date of Conference: 16-19 March 2005

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