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Contrast enhancement of the lateral skull X-ray images is very important in orthodontic practice, cephalometric evaluation and craniofacial landmarking. In this paper we present computational techniques involving contrast enhancement of two-dimensional digitized X-ray images. The algorithm is developed based on the use of local heterogeneity measures of pixel distribution. Image enhancement is accomplished by an adaptive gray scale pixels transformation depending on results of local heterogeneity contribution measures. The proposed approach was tested on different images and the results prove that the proposed method has better performance the existing conventional methods.