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A systematic comparative study on the mutual coupling (S21) between dielectric resonator antennas (DRAs) and microstrip patch antennas is presented. The mutual coupling between two cylindrical probe-fed DRAs is studied for different radius to height (a/L) ratios. It is found that the mutual coupling decreases with the radius to height ratio. Comparison between mutual coupling of probe-fed cylindrical DRAs and circular microstrip patch antennas with different dielectric substrates are also studied. The mutual coupling between DRAs is 2 dB stronger than between microstrip patch antennas when the patch is etched on a dielectric substrate of a dielectric constant close to the permittivity of the DRA. The mutual coupling of the circular patch antennas reduces with the dielectric constant of the substrate.