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We investigate path loss and fading compensation methods for TCP throughput enhancement over wireless channel. The scenario considered is that of a high-mobility system undergoing fast fading, TCP throughput modeling is done for the purpose and channel compensation along the trajectory of a high speed train is discussed. Interpretation of the proposed power adaptation measures to make deployment decisions for wireless infrastructure along the train track, is then presented. It is shown that with suitable choice of power adaptation measures, TCP performance degradation over wireless channel can be prevented.